Uso da biologia molecular nas ciências forense

Abstract

Abstract: Molecular biology tools have increased the forensic scientist's ability to characterize biological evidence to the point where it is possible to analyze tiny samples and achieve high levels of individualization. In this case study, we describe key forensic biological evidence that is being or is likely to be filled in by molecular biology tools. Data collected from the study point to results such as knowledge gaps and new directions were identified where molecular biology is likely to guide the field of forensic science. We identified some of these areas where further development is needed: improving current typing limits for low quantity and quality samples; improve the efficiency of sample recovery and extraction; convert current STRs into mini-STRs; select and validate new mini-STRs; select and validate a variety of SNPs for different applications; multiplexing enhancement; development of automation for high throughput; development of expert systems for data interpretation; develop sequencing capabilities for screening microorganism genomes; and field tests. We conclude that the future of molecular biology for forensic science is exciting and dynamic. There is still much to be achieved and the developments in molecular biology will be essential to help solve crimes and identify missing people.